Method to Identify Drugs, Moiety or Diagnostic

Method to Produce a Plurality of Antibodies

Portable Apparatus For Sample Analysis

Method to Determine Immune Status

Flow Thru Test w/ Pressure Indicator

Data Driven Outcomes

Remote Medication Delivery System

Remote User Monitoring System

60/608,342 Filed 9/9/04 Closed

60/608,526 Filed 9/9/04 Closed

60/863,241 Filed 10/27/06 Closed

FF

PCT/US2007/082499 Filed 10/25/07 Closed

60/845,395 Filed 9/18/06 Closed

61/814,916 Filed 4/23/13 Closed

61/791,218 Filed 5/15/13 Closed

14/979,742 Filed 12/23/14 Pending

14/979,889 Filed 12/28/15 Pending

↓CONV

↓CONV

↓CONV

↓NP

↓CONV

↓CONV

↓FF

11/221,038 Filed 9/7/05 Abandoned

11/221,252 Filed 9/7/05 Abandoned

11/924,033 Filed 10/25/07 Abandoned

11/856,825 Filed 9/18/07 Abandoned

PCT/US14/35073 Filed 4/23/14 Closed

GB2526749 Filed 9/9/14 Published

CN 200780039901.X CN Z200780039901.X Published

↓CONT

↓CONT

↓CONT

↓CONT

↓CONT

↓FF

HK 10103654.9 HK 1137813 Published

12/769,036 Filed 4/28/10 Pending

13/253,366 Filed 10/5/11 US 9,573,990

13/248,307 Filed 9/29/11 US 8,920,725

14/492,641 Filed 9/22/14 Pending

14/786,272 Filed 9/9/14 US 9,588,114

WO2014144749A1 Filed 9/9/14 Published

EP 07854420.2 Abandoned

↓CONT

↓CONT

US 14/212,429 Filed 3/14/14 Pending

14/553,011 Filed 11/25/14 US 9,170,258

IP 785/MUMNP/2009 IN 279743 Published

MO J/1298 MO J/001298 Published

Areas of Intellectual Property creation as barrier to entry for its competitors

Key Patentable Concepts

·        Sample Analysis

·        Plurality of Isolated Antibodies to a Plurality of Cognate Antigens

·        Identifying Drugs, Targeting Moieties or Diagnostics

·        Determining the Immune Status of a Subject

·        Flow Through Testing System with Pressure Indicator

·        Novel biomarker candidates

·        Antibodies

·        Proteins

·        Diagnostic testing

 

 

Parallax / Montecito BioSciences, Ltd. Patents and Applications

Background: Parallax intends to seek Intellectual Property protection for all supporting products such as novel biomarker candidates, antibodies, proteins, and diagnostic tests surrounding the Company’s core indication areas, in order to create a barrier to entry for its competitors.

US Patent Application US 11/924,033 “Portable Apparatus for Improved Sample Analysis” has generated 2 issued Patents 8,920,725 and 9,170,258 providing protection of its Test Platform and its mobile version of its VT-1000 Desktop Analyzer. The US Patent Application US 11/924,033 “Portable Apparatus for Improved Sample Analysis” was filed to protect the process of testing with the Company’s Target Antigen Detection System Cartridge and a mobile version of the Company’s VT-1000 Desktop Analyzer. Currently, Patent Application US 11/924,033 has also resulted in a Foreign Patent Granted in China, Hong Kong, with an additional foreign application pending in India.

The IPN will provide Intellectual Property protection recommendations for all of its Intellectual Property, open patent applications and products, both domestically and internationally.  

Open Applications available for continuation filings:

2b. US13/253,366 - Title: “Method of Producing a Plurality of Isolated Antibodies to a Plurality of Cognate Antigens”

3b. US12/769,036 Title: “Method of Identifying Drugs, Targeting Moieties or Diagnostics”

4b. US14/492,641 Title: “Method for Determining the Immune Status of a Subject”

5b. 14/786,272 Title: Flow Through Testing System with Pressure Indicator

 

Portfolio Overview

Issued Portfolio / Applications Pending or Abandoned

1a. *ABANDONED

1a. US11/924,033 “Portable Apparatus for Improved Sample Analysis”

The present invention is an improved apparatus for sample analysis. The apparatus employs an assay component containing a membrane having one or a plurality of analyte-specific binding agents attached thereto, a means for absorbing liquid, and a piston means for drawing analytes through said membrane into said means for absorbing liquid. The apparatus is configured to be portable and provide a detector for detecting binding of an analyte to an analyte-specific binding agent, a plurality of data acquisition components, and a computer for integrating, analyzing and storing the detected analyte specific binding and acquired data.

 

[1]Patent Application US11/924,033 was being prosecuted worldwide.  The now abandoned EPO Application No. 07854420.2 was filed in the following designee countries; Austria, Belgium, Bulgaria, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Luxembourg, Monaco, Netherlands, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, Liechtenstein, Turkey and the United Kingdom.  The Company filed and was granted in Hong Kong its Hong Kong Patent Application No. 10103654.9.  The Company filed and is pending in India under a New Indian Patent Application based on the PCT Application No. PCT/US2007/082499.

https://www.google.ie/patents/US20090010804?dq=US11/924,033&hl=en&sa=X&ved=0ahUKEwimsK_rq7rQAhUHh1QKHV2tBB8Q6AEIHTAA

 

1b. Issued Patent

 

1b. 8,920,725 - US13/248,307 Title: “Portable Apparatus for Improved SampleAnalysis”

This family of cases discloses and claims the handheld TargetAnalyzer™ device, which is capable of housing and analyzing two assay cassettes. The claimed device optionally features wired or wireless data transfer and multiple data acquisition components including a keypad, a touch-pad, a barcode wand and / or a finger print reader. US13/248,307, filed: September29, 2011.

This case issued as US Patent No.8,920,725.

US14/553,011, filed: November25, 2014 This case issued as US Patent No.9,170,258.

Chinese Application Serial No.:200780039901.X,filed October25,2007. This case issued as CNZ200780039901.X. Hong Kong Application Serial No: 10103654.9, filed October 25, 2007.

This case issued as HK1137813.

Macoa Application No: MOJ/1298, filed October25, 2007. This case issued as MOJ/001298.

Indian Application No: IN785/MUMNP/ 2009, filed October25, 2007.This case is currently pending.

Priority: US11/924,033 filed October25, 2007; US60/863,241,filedOctober27,2006.

https://patents.google.com/patent/US8920725B2/en

 

1c. Issued Patent

 

1c. 9,170,258 - US14/553,011 Title: “Portable Apparatus for Improved SampleAnalysis”

This family of cases discloses and claims the handheld TargetAnalyzer™ device, which is capable of housing and analyzing two assay cassettes. The claimed device optionally features wired or wireless data transfer and multiple data acquisition components including a keypad, a touch-pad, a barcode wand and / or a finger print reader. US13/248,307, filed: September29, 2011. This case issued as

US Patent No. 8,920,725

US14/553,011, filed: November25, 2014 This case issued as US Patent No.9,170,258.

Chinese Application Serial No.:200780039901.X, filed October25,2007. This case issued as CNZ200780039901.X. Hong Kong Application Serial No: 10103654.9, filed October 25, 2007. This case issued as HK1137813.

Macoa Application No: MOJ/1298, filed October25, 2007. This case issued as MOJ/001298.

Indian Application No: IN785/MUMNP/ 2009, filed October25, 2007.This case is currently pending.

Priority: US11/924,033 filed October25, 2007; US60/863,241, filed October27, 2006.

https://patents.google.com/patent/US9170258B2/en

1d. Foreign Patent Granted:

1d. CNZ200780039901.X / CN 1015558302A On August 23, 2013 the Company was notified that its Chinese Patent Application No. 200780039901.X “Portable Apparatus for Improved Sample Analysis” has been granted by the States Intellectual Property Office of the Peoples Republic of China. This Patent Application covers the Company’s SPARKS Mobile hand held analyzer in conjunction with the TARGET System Test Cartridge. Patents have also been granted in the countries of Hong Kong and Macau.

1e. Foreign Patent Granted:

1e. HK1137813 / HK10103654.9 The Company filed in Hong Kong its Hong Kong Patent Application No. 10103654.9. has been granted HK1137813

1g. Foreign Patent Granted:

1g. Macau MO J/001298 has been granted

https://patents.google.com/patent/CN101558302B/en

1g. Pending Foreign Application

1g. The Company filed in India under a New Indian Patent Application based on the PCT Application No. PCT/US2007/082499.

 

2a. ABANDONED

 

2a. US2006051348 - 11/221,252 “Method of Producing a Plurality of Isolated Antibodies to a Plurality of Cognate Antigens”

The present invention relates to a method for producing high affinity antibodies that are antigen-specific. The method involves binding a plurality of antibody-producing B-cells from a mammal to a plurality of cognate antigens; sorting the bound antibody-producing B-cell and cognate antigen; amplifying nucleic acid sequences encoding each antibody, or fragment thereof, from the B-cells; and expressing the each antibody in a protein expression system. Antibodies produced in this manner are useful in diagnostic and therapeutic applications.

https://www.google.ie/patents/US20060051348

 

2b. Pending

 

2b. US13/253,366 - Title: “Method of Producing a Plurality of Isolated Antibodies to a Plurality of Cognate Antigens”

This family of cases covers a technique for obtaining a population of antibodies produced by B-cells, without any a priori information about the population of antibodies, and use of the same in an array for profiling antigen expression. US13/253,366, filed: October5, 2011. This case is currently pending.

Priority: US11/221,252, filed September7, 2005; US60/608,526, filed September 9, 2004.

https://patents.google.com/patent/US20120029171A1/en

3a. ABANDONED

3a. US2006052948 - 11/221,038 “Method of Identifying Drugs, Targeting Moieties or Diagnostics”

The present invention relates to a method for identifying a binding agent or epitope for use in drug design, drug targeting or diagnostics. The method employs contacting and sorting binding agents and cognate epitopes from collections thereof, characterizing the binding agent and cognate epitope, detecting the level or location of the epitope in a sample using the binding agent, and correlating the level or location of the epitope in the sample with the presence or stage of a disease or condition to identify novel drugs, targeting moieties, or diagnostic agents.

https://www.google.ie/patents/US20060052948?dq=US2006052948+-+11/221,038&hl=en&sa=X&ved=0ahUKEwi9k8nEq7rQAhXGlVQKHdD_CrkQ6AEIHTAA

 

 

3b. PENDING

 

3b. US12/769,036 Title: “Method of Identifying Drugs, Targeting Moieties or Diagnostics”

 

This family of cases covers a technique for obtaining a population of antibodies that specifically binds to a corresponding population of antigens, without any a priori information about either population. The antigens identified by the method are subsequently characterized and correlated with the presence or stage of a disease or condition there by serving as a target for drug design, drug targeting or diagnostics.

 

US Application Serial No.: US12/769,036, filed April28, 2010. This case is currently pending.

Priority: US11/221,038, filed September7, 2005; US60/608,342, filed September9, 2004.

https://patents.google.com/patent/US20100210824A1/en

 

4a. Abandoned

4a. US11/856,925 “Method for Determining the Immune Status of a Subject”

 

The present invention is a method for using levels of soluble Clusters of Differentiation (CD) proteins, or cell surface-localized CD proteins extracted from T lymphocytes for determining the immune status of a subject. The present invention also a kit containing a CD protein extraction means and at least one antibody which specifically binds a CD protein for use in carrying out the method of the invention.

https://www.google.ie/patents/US20080085532?dq=US11/856,925&hl=en&sa=X&ved=0ahUKEwi83s3fq7rQAhXGlVQKHdD_CrkQ6AEIHTAA

 

4b. Pending

4b. US14/492,641 Title: “Method for Determining the Immune Status of a Subject”

This family of cases covers a technique and kit for assessing immune status, e.g., in HIV patients, based upon the amount of soluble or surface-localized CD3,CD4, andor CD8 protein present in a patient sample.

This method and kit is an alternative to conventional cell sorting technologies.

US Application Serial No: 14/492,641 filed September 22, 2014. This case is currently pending.

Priority: US11/856,925 filedSeptember18,2007;US60/845,395,filedSeptember18,2006.

https://patents.google.com/patent/US20150011418A1/en

 

5a Closed

5a. PCT/US14/35073 / US61/814,916 Title: Flow Through Testing System with Pressure Indicator

This family of cases covers an improved assay cassette with pressure-sensitive microcapsules for ensuring that a sufficient reduction in pressure is achieved there by maximizing contact between the sample and analytic compound. US Application Serial No: 14/786,272 filed October22, 2015. This case is currently pending.          Priority: PCT/US14/35073, filed April 23, 2014; US61/814,916 filed April 23, 2013.

 

5b. Pending

5b. 14/786,272 Title: Flow Through Testing System with Pressure Indicator

A device for performing immunoassays on analytes. The device includes an immunosorbent membrane, an absorbent material, a piston component located below said absorbent material to draw analytes in a sample through the immunosorbent membrane into the absorbent material, and discrete groups of pressure-sensitive microcapsules located on the immunosorbent membrane. https://patents.google.com/patent/US20160084831A1/en

 

 

US20140280136 Platform for optimizing data driven outcomes 

Also published as WO2014144749A1 Platform for optimizing data driven outcomes

Also published as GB2526749 Platform for optimizing data driven outcomes

A computer based method for tracking outcome specific data specifically for optimizing, managing, and tracking data driven outcomes.   

Process utilizes a multi-dimensional platform to facilitate data-driven outcomes processes through assessment, goal development, data tracking, graphing, and re-evaluation.

The process allows for optimization of best practices, successful actions, and success based plan execution, which is identified through automatic data-mining and analysis as well as user specified parameters, algorithms, and analytics.

The process can be utilized by a client, patient, student, service provider, program, product, service, device, organization, business, department, or so forth.

The tool can be utilized across various industries for client behavior management, educational instruction, school improvement activities, program evaluation, organizational key performance indicators, financial management, weight management, tracking insurance claims, or so forth.

 

 

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